Monday, October 13, 2025

The best strategy to take over-the-counter painkillers? Learn the labels : NPR

Thousands and thousands of People take over-the-counter ache meds, however many do not perceive how they work or the dangers concerned in taking them. We take a look at finest practices for taking non-prescription ache medicine.



AYESHA RASCOE, HOST:

In the event you get a headache in the course of the day, what’s your first line of protection? For lots of People, the reply is over-the-counter painkillers like Tylenol or Advil. However let’s be trustworthy, we’re not at all times good at following the label. One 2018 examine discovered that just about 1 in 5 people who take NSAIDs – that’s, nonsteroidal anti-inflammatory medicine like Aspirin or ibuprofen – exceed the each day advisable dose, and that would result in large well being issues. Life Equipment’s Andee Tagle is right here to let you know what you must find out about OTC painkillers. Good morning.

ANDEE TAGLE, BYLINE: Good morning, Ayesha.

RASCOE: We have all had that horrible headache that does not allow us to sleep, or if I’ve the slightest headache, I simply seize no matter’s within the drugs cupboard. Is {that a} dangerous concept?

TAGLE: The factor concerning the two important sorts of OTC painkillers – there are these NSAIDs you simply talked about, Motrin or Aleve, after which there’s acetaminophen, mostly referred to as Tylenol – is that there is a restrict to how a lot ache they will deal with. In the event you take greater than the advisable dosage, you are not essentially getting any extra ache aid, and also you’re growing your threat of negative effects.

RASCOE: Yeah, that sounds sort of dangerous.

TAGLE: Oh, yeah. I talked about this with Dr. Trisha Pasricha. She’s an teacher of drugs at Harvard Medical College. And as a gastroenterologist, she additionally has a whole lot of issues about NSAID use specificall since you do not even at all times must misuse these meds to expertise critical negative effects like injury to your kidneys or gastrointestinal bleeding from persistent long-term use.

TRISHA PASRICHA: You possibly can take that applicable protected quantity not more than what’s the each day advisable dose, and there could be injury over time, even whenever you do every little thing that is supposedly right. My recommendation is that at all times take the smallest quantity that you just want for the shortest interval potential.

TAGLE: And beginning low and sluggish additionally applies for acetaminophen as a result of it may be laborious in your liver.

RASCOE: So that you talked about acetaminophen and NSAIDs. These are the 2 large choices for over-the-counter ache killers. When do you have to use one over the opposite?

TAGLE: So the principle distinction between the 2 is how they work in your physique to deal with ache. Acetaminophen or Tylenol is known to work by elevating your physique’s ache threshold and regulating your physique temperature, so it’s extremely efficient for fevers particularly and can be used for ache aid in a lot of different meds. Now, NSAIDs – model names Motrin or Aleve – work all through your physique to scale back irritation, and in contrast to acetaminophen, there are a whole lot of differing kinds to select from.

So for instance, say you have got persistent ache from an outdated harm that flares up. You would possibly attain for naproxen as a result of it has an extended launch time, that means much less capsules, longer aid all through the day. However when you have the flu, you may want faster hits of ache aid extra usually, so that you go for ibuprofen, possibly. Usually, folks discover NSAIDS simpler than acetaminophen for ache aid, however there are additionally extra potential negative effects, particularly to your coronary heart and your intestine.

RASCOE: So Andee, is the takeaway right here simply to keep away from over-the-counter painkillers, like, altogether?

TAGLE: Completely not, Ayesha. Over-the-counter medicine have been regulated and permitted by the FDA to be used by most people, so that they’re protected. You do not have to be scared. You simply have to truly use as directed. That stated, Pasricha says to recollect, capsules aren’t your solely ache aid choice. Many NSAIDS can be found in topical type, for instance, like gels or patches, and people can provide related aid with out all of the potential negative effects.

PASRICHA: Simply discover what the opposite choices are for you that may really even management your ache extra reliably.

TAGLE: There are additionally fully nonmedicated cures, like chilly packs or heating pads to ease again ache or yoga for complications and stress aid.

RASCOE: Life Equipment’s Andee Tagle, thanks a lot for becoming a member of us.

TAGLE: I hope it is useful.

(SOUNDBITE OF SONG, “EVERYBODY HURTS”)

R E M: All people hurts typically.

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